Mescaline + Trichocereus species

Medium confidence: We're pretty sure this risk rating is right, but we aren't certain.

Low risk synergy: This combination will enhance the effects of each psychoactive, or sometimes give new effects.

Reports of people trying this psychoactive combination

“The combined effects of mescaline and MDMA were incredible. It was like a typical mescaline trip, but with all the MDMA-like qualities dramatically enhanced. The mescaline also seemed to buffer the MDMA come-on, making it more gentle and gradual, with the two drugs melding their effects into a warm, fuzzy trip. It felt really really good. It was also a very deep trip…” Erowid.

Related research publications

We are yet to identify a research publication reporting on this combination. If you know of a publication that demonstrates the risk rating of this combination, please share the publication with us.

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