Ketamine + Opioids

High confidence: There is good evidence to support the risk rating of this combination.

Significant risk: Danger! This is our most dangerous combination rating.

Reports of people trying this psychoactive combination

”In moderation it isn’t particularly unsafe, but aside from pain relief, I personally feel it is a waste of opioids (especially good opioids, like oxycodone). Dissociatives blunt opioids in my experience.” Bluelight

Related research publications

We are yet to identify a research publication reporting on this combination. If you know of a publication that demonstrates the risk rating of this combination, please share the publication with us.

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