Cocaine + Opioids

Cocaine powder by Drug Enforcement Administration (DEA)
Cocaine powder by Drug Enforcement Administration (DEA)
Opioids by GeoTrinity
Opioids by GeoTrinity

Medium confidence: We're pretty sure this risk rating is right, but we aren't certain.

Significant risk: Danger! This is our most dangerous combination rating.

Reports of people trying this psychoactive combination

”The danger with mixing opiates and strong stimulants is that if you take them at the same time you might take too much of one. Then when the one with the shortest duration wears off you will either be dangerously overstimulated or dangerously sedated.” Bluelight.

”As long as your tolerance is at the proper level for those doses, then no. There is no inherent negative interaction between opiates and cocaine, the only risk is overdose.” Bluelight.

We are yet to identify a research publication reporting on this combination. If you know of a publication that demonstrates the risk rating of this combination, please share the publication with us.

Disagree? Found a typo? Got more info? Edit this page or email us


This website may contain errors. If you find one, please help us fix it.

Psychoactive use is embedded in cultural and environmental contexts and should be treated with caution and respect.

We promote psychoactive science and do not endorse illegal activity. We are fully compliant with NSW and federal Australian law.