Caffeine + Opioids

High confidence: There is good evidence to support the risk rating of this combination.

Low risk no synergy: This combination won't do much more than the individual effects of the psychoactives involved.

Reports of people trying this psychoactive combination

“caffeine (coffee especially) seems to actually enhance my opiate experience.” Bluelight.

Related research publications

We are yet to identify a research publication reporting on this combination. If you know of a publication that demonstrates the risk rating of this combination, please share the publication with us.

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